Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Aug 31;28(1):2251237. doi: 10.1080/13510002.2023.2251237

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

PMC Copyright notice

Figure 7. — Treatment with LIPUS strengthened ferroptosis-related antioxidative stress and improved the function of mitochondria in the ADR-induced CKD rat. (A) The protein expression levels of glutathione peroxidase 4 (GPX4), solute carrier family 7 member (SLC7A11) and acyl-CoA synthetase long-chain family member 4 (ACSL4) in rat kidney tissue were assayed by western blotting (WB). Relative expression levels of GPX4 (B), SLC7A11 (C) and ACSL4 (D) in each group. The mRNA expression level of GPX4 (E) in rat kidney tissue were proved by real-time quantitative polymerase chain reaction (RT-qPCR). The levels of total superoxide dismutase (T-SOD) (F), glutathione (GSH) (G) and glutathione peroxidase (GSH-Px) (H) in rat kidney tissue were assayed by enzyme linked immunosorbent assay (ELISA). (I) Ultrastructural alterations of tubular epithelial cells (TECs) were analysed using transmission electron microscopy. scale bar, 2.0μm/0.2μm. Abbreviations: BM, basement membrane; FP, foot process; M, mitochondria. Data represent the mean ± standard error of the mean (SEM) for 6 rats in each group. *p < 0.05, ** p < 0.01, ***p < 0.001, **** p < 0.0001.