Table 2.
Outcomes according to admission systolic blood pressure*.
| All patients, n = 539 | aOR/β (95% CI) † | p-Value for interaction ‡ | |
|---|---|---|---|
| Death at 90 days – n (%) | 98 (18%) | 1.08 (0.97–1.20) | 0.19 |
| NIHSS at 5–7 days – median (IQR) | 4 (1–11) | 0.09 (−0.26–0.45) | 0.12 |
| Successful reperfusion (eTICI 2b-3) – n (%) | 388 (81%) | 1.00 (0.91–1.10) | 0.58 |
| sICH – n (%) | 30 (6%) | 1.09 (0.93–1.27) | 0.29 |
| Any intracranial haemorrhage – n (%) | 174 (36%) | 1.02 (0.94–1.11) | 0.04 § |
| Final lesion volume on follow-up imaging – median (IQR) | 20 (6–74) | 1.17 (−3.03–5.36) | 0.36 |
| Stroke progression – n (%) | 15 (3%) | 1.14 (0.92–1.41) | 0.78 |
eTICI: extended Thrombolysis in Cerebral Infarction; NIHSS: National Institutes of Health Stroke Scale; sICH: symptomatic intracranial haemorrhage.
*
Number of missing values: SBP: 2; NIHSS 5–7d: 56; successful reperfusion: 59; any intracranial haemorrhage: 52; final lesion volume: 63.
†
For all outcomes restricted cubic spline transformation allowing 3 knot for SBP did not improve model fit. Adjusted ORs and 95% CIs are estimated per 10 mmHg change in SBP.
‡
SBP*prior IVT.
§
Because of a significant interaction test (p < 0.05), IVT subgroup analysis was performed for the outcome any intracranial haemorrhage. Prior IVT – aOR: 1.10 (95% CI: 0.98–1.24); no prior IVT – aOR:0.95 (95% CI: 0.84–1.08).