Table 1.
Cohort characteristics.
| Overall | |
|---|---|
| n | 133 |
| Clinical characteristics | |
| Age (median (IQR)) | 74 (63–84) |
| Sex (%) | |
| Female | 61 (46%) |
| Medical history (%) | |
| Atrial fibrillation | 31 (23%) |
| Hypertension | 78 (59%) |
| Hypercholesterolaemia | 80 (60%) |
| Diabetes | 30 (23%) |
| Ischaemic stroke or TIA | 23 (17%) |
| Myocardial infarction | 17 (13%) |
| Pre-stroke mRS (%) | |
| mRS 0–2 | 110 (83%) |
| mRS 3–5 | 23 (17%) |
| Prehospital characteristics | |
| Onset-to-door time (median (IQR))* | 104 (48–357) |
| Last known well-to-door time (median (IQR)) | 428 (178–747) |
| Witnessed onset-to-door time (median (IQR)) | 54 (39–83) |
| Onset-to-door time within 6 h (%) | 100 (75%) |
| Type of onset (%) | |
| Last known well | 57 (43%) |
| Witnessed onset | 76 (57%) |
| Hospital characteristics and assessments | |
| Primary stroke centre (%) | |
| Hospital 1 | 32 (24%) |
| Hospital 2 | 21 (16%) |
| Hospital 3 | 16 (12%) |
| Hospital 4 | 35 (26%) |
| Hospital 5 | 19 (14%) |
| Hospital 6 | 10 (8%) |
| Presentation during office hours (%) | 60 (45%) |
| Blood pressure | |
| Systolic blood pressure, mmHg (mean (SD)) | 151 (25.5) |
| Diastolic blood pressure, mmHg (mean (SD)) | 87 (17.5) |
| Hypertension (%) | 17 (14%) |
| Administration of IVT at PSC (%) | 65 (49%) |
| NIHSS at intervention centre (median (IQR)) | 14 (8–19) |
| Imaging characteristics | |
| Acquisition of CTP at PSC (%) | 29 (22%) |
| Occlusion side (%) | |
| Left | 71 (53%) |
| Right | 62 (47%) |
| Occlusion segment (%) | |
| ICA-T/M1 | 77 (58%) |
| M2 | 56 (42%) |
| Logistical and procedural characteristics | |
| Location of initial patient workup (%) | |
| CT-room | 101 (76%) |
| ED-room | 32 (24%) |
| Location of CT-room (%) | |
| ED based | 54 (41%) |
| Elsewhere in hospital | 79 (59%) |
| Transfer notification order (%) | |
| Ambulance first | 56 (42%) |
| Intervention centre first | 77 (58%) |
| Stroke alarm notification (%) | |
| ED notification | 85 (64%) |
| Neurologist notification | 48 (36%) |
| Workflow times, min | |
| Door-in-door-out time (median (IQR)) | 66 (52–83) |
| Door-in-door-out time within 1 h (%) | 50 (38%) |
| Final treatment | |
| Endovascular thrombectomy (EVT) (%) | 105 (79%) |
| Digital subtraction angiography (DSA) behind digital subtraction angiography without EVT (%) | 5 (4%) |
| Groin-puncture without DSA or EVT (%) | 1 (1%) |
| No DSA or EVT (%) | 22 (16%) |
IQR: interquartile range; TIA: transient ischaemic attack; mRS: modified Rankin Scale; SD: standard deviation; IVT: intravenous thrombolysis; PSC: primary stroke centre; NIHSS: National Institutes of Health Stroke Scale; CTP: computed tomography perfusion scan; NCCT: non-contrast-enhanced computed tomography scan; CTA: computed tomography angiography scan.
Data are reported as n (%), mean (SD) or median (IQR).
Onset time is defined as either time of symptom onset if witnessed, or last known well if unwitnessed. Missing data: Systolic blood pressure: 10, diastolic blood pressure: 10, hypertension: 10, NCCT-acquisition time: 5, CTA-acquisition time: 7, door-to-NCCT time: 5, NCCT-to-CTA time: 8, CTA-to-ambulance notification time: 7. All time intervals were known in 125 patients.