Table 1.

TREM2 Variants. Different TREM2 variants and its effects on the TREM2-Ligand affinity

S. No	TREM2 Variants	Effect on TREM2 –Ligand affinity
1	R47H	Lowers the binding affinity
2	R62H	Lowers the binding affinity
3	W191X	NA
4	E151K	NA
5	L211P	NA
6	G145T	Lowers the binding affinity
7	T96K	Increase the binding affinity
8	T66M	Lowers the binding affinity
9	Y38C	Lowers the binding affinity
10	Q33X	Lowers the binding affinity