Table 1.

Patents of BACE2 inhibitors published between 2013-present

Year of Publication	Title & (Patent Number)	Target(s)	Reference(s)
2017	Bace-2 inhibitory compounds and related methods of use (WO2017066742A1)	BACE2	[73]
2016	Compounds for inhibition of memapsin 1 (US9512099B2)	BACE2	[64, 65, 72]
2016	1,4 oxazines as BACE1 and/or BACE2 inhibitors (US9242943B2)	BACE1 or BACE2	[71]
2015	Spiro-[1,3]-oxazines and spiro-[1,4]-oxazepines as BACE1 and/or BACE2 inhibitors (US9079919B2)	BACE1 or BACE2	[70]
2015	Halogen-alkyl-1,3 oxazines as BACE1 and/or BACE2 inhibitors (US8987255B2)	BACE1 or BACE2	[69]
2015	Cyclopropyl-fused-1,3-thiazepines as BACE1 and/or BACE2 inhibitors (US8927535B2)	BACE1 or BACE2	[68]
2013	N-[3-(5-amino-3,3a,7,7a-tetrahydro-1H-2,4-dioxa-6-aza-inden-7-yl)-phenyl]-amides as BACE1 and/or BACE2 inhibitors (US8404680B2)	BACE1 or BACE2	[67]