Fig. 5.

Effects of Agent Orange herbicidal toxin exposures on AβPP and AβPP-Aβ. Human PNET2 cells treated for 48 h with Vehicle, 250μg/ml 2,4,5-T or 250μg/ml 2,4-D were analyzed for (A) AβPP, (B) Aβ immunoreactivity by duplex ELISA with results normalized to large acidic ribosomal protein (RPLPO). Each group included 6 replicate cultures. Results were analyzed by one-way ANOVA (Table 5). Significant (p < 0.05) and statistical trend (0.05 < p<0.10) results of repeated measures post hoc Tukey tests are shown. 2,4,5-T, 2,4,5-trichlorophenoxyacetic acid; 2,4-D, 2,4-dichlorophenoxyacetic acid.