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Kaplan–Meier curve for overall survival (A) and progression-free survival (B) according to use of PPIs in patients with SSc-ILD. Analysis of Set 2. Progression defined as decline in FVC of ≥10%, decline in DLCO of ≥15%, or death. Shading represents confidence intervals. DLCO: diffusing capacity of the lung for carbon monoxide; FVC: forced vital capacity; ILD: interstitial lung disease; PPI: proton-pump inhibitor; SSc-ILD: SSc-associated interstitial lung disease
