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. 2023 Jun 1;22(2):62–69. doi: 10.1097/CLD.0000000000000050

TABLE 2.

Histological features in INCPH (PSVD) with description and alternative terminologies4

Serial number Specific features Alternative names Description
1 Obliterative portal venopathy Phlebosclerosis, PV obliteration, PV stenosis, hepatoportal sclerosis Incomplete or complete luminal narrowing of PV branches along with PV wall thickening and fibrosis
2 Nodular regenerative hyperplasia Micronodular changes of hepatic parenchyma without any significant fibrosis
3 Incomplete septal fibrosis/cirrhosis Fine fibrous septa that arise from a PT and terminate blindly within a hepatic lobule without any definitive bridge to central veins or other PT
Nonspecific features Alternative names Description
1. PT abnormalities Herniated PV Aberrant vessels, shunt vessels A PV branch originating from PT abutting the adjacent hepatic parenchyma without a rim of intervening connective tissue
Periportal abnormal vessels Aberrant vessels, cavernous transformation, periportal shunting vessels Single or multiple thin-walled vascular channels of variable caliber in close contact with the PT but not within
Hyper-vascularized PT Multiplicity of PVs, PT angiomatosis, angiomatoid lesion, angiomatous transformation of PT Increased number of PV branches within PT
2 Architectural disturbance Irregular distribution of PTs and central veins
3 Nonzonal sinusoidal dilatation Sinusoidal lumen (nonzonal) wider than a single liver cell plate
4 Mild perisinusoidal fibrosis Fibrosis around the sinusoids

Abbreviations: INCPH, idiopathic noncirrhotic portal hypertension; PSVD, portosinusoidal vascular disorder; PT, portal tract; PV, portal vein.