Table 6.
TNF-α 308 G>A (rs1800629) Acne Presentation
| Allele | Acne | Controls | OR (95% CI) | P | ||
|---|---|---|---|---|---|---|
| Study | A(%) | G(%) | A(%) | G(%) | ||
| Akoglu et al, 2019 (Turkey)19 | 32(17.8) | 148(82.2) | 17(28.3) | 43(71.7) | 0.55(0.28;1.08) | – |
| Baz et al, 2008 (Turkey)31 | 51(22.6) | 175(77.4) | 15(6.6) | 213(93.4) | 4.14(2.25;7.61) | – |
| Al-Shobailiet et al, 2012 (Saud Arabia)32 | 63(19.2) | 265(80.8) | 166(21.3) | 614(78.7) | 0.88(0.64;1.22) | – |
| Grech et al, 2014 (Greece)33 | 31(8.4) | 339(91.6) | 17(5.2) | 313(94.8) | 1.68(0.91;3.1) | – |
| Aisha et al, 2016 (Pakistan)35 | 105(37.5) | 175(62.5) | 90(28.1) | 230(71.9) | 1.53(1.07;2.19) | <0.02 |
| Sobjanek et al, 2009 (Poland)36 | 20(11.9) | 148(88.1) | 27(18) | 123(82) | 0.62(0.33;1.15) | – |
| Szabó et al, 2011 (Hungary and Romania)37 | 80(17.5) | 378(82.5) | 32(12.6) | 220(87.4) | 1.46(0.94;2.27) | – |
Notes: The analysis was performed using the allele model (minor allele vs major allele), that is, A vs G. P < 0.05 is statistically significant. – means that there is no data in the original paper; numbers with percentages are in parentheses.