Table 10.
RETN−420 C>G (rs1862513) Acne Presentation
| Allele | Acne | Controls | OR(95% CI) | P | ||
|---|---|---|---|---|---|---|
| Study | G(%) | C(%) | G(%) | C(%) | ||
| Chen et al, 2022 (China)27 | 413(67.5) | 199(32.5) | 287(46.9) | 325(53.1) | 2.35(1.86;2.96) | <0.001 |
| Younis et al, 2016 (Pakistan)42 | 592(56) | 468(44) | 556(51.0) | 544(49.0) | 1.24(1.05;1.47) | 0.013 |
| Al-Hilali et al, 2016 (Iraq)43 | 85(86.7) | 13(13.3) | 40(80.0) | 10(20.0) | 1.63(-) | – |
| Hussain et al, 2015 (Pakistan)44 | 75(20.9) | 285(79.1) | 44(12.2) | 316(87.8) | 1.89(1.23;2.89) | 0.002 |
| Shehata et al, 2021 (Egypt)45 | 29(36.3) | 51(63.7) | 11(13.7) | 69(86.3) | 3.57(1.63;7.80) | 0.001 |
| Akcılar et al, 2022 (Turkey)46 | 99(52.7) | 89(47.3) | 100(53.2) | 88(46.8) | 0.98(-) | – |
Notes: The analysis was performed using the allele model (minor allele vs major allele), that is, G vs C. P < 0.05 is statistically significant. - means that there is no data in the original paper; numbers with percentages are in parentheses.