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. 2023 Aug 18;13:1155650. doi: 10.3389/fonc.2023.1155650

Table 7.

Cox proportional hazard regression models for cause-specific survival for male lung and bronchus cancer patients by detailed occupation status: Florida Cancer Data System (1981–2014).

Occupation Univariate models Multivariable models
Model 1 Model 2
HR (95% CI) p-value aHR (95% CI) p-value aHR (95% CI) p-value
Non-firefighters 1.00 (reference) 1.00 (reference)
Firefighters 0.82 (0.75, 0.89) <0.001 0.84 (0.77, 0.91) <0.001
Non-firefighters 1.00 (reference) 1.00 (reference)
Volunteer firefighters 0.84 (0.70, 1.01) 0.063 0.76 (0.63, 0.91) 0.003
Career firefighters 0.81 (0.74, 0.89) <0.001 0.86 (0.79, 0.95) 0.002
Volunteer firefighters 1.00 (reference) 1.00 (reference)
Career firefighters 0.96 (0.79, 1.18) 0.718 1.14 (0.93, 1.39) 0.213
Firefighters 1.00 (reference) 1.00 (reference)
Non-firefighters 1.22 (1.13, 1.33) <0.001 1.20 (1.10, 1.30) <0.001
Firefighters 1.00 (reference) 1.00 (reference)
White collar 1.06 (0.98, 1.16) 0.166 1.11 (1.02, 1.21) 0.016
Blue collar 1.17 (1.08, 1.28) <0.001 1.15 (1.05, 1.25) 0.002
Service 1.13 (1.02, 1.24) 0.016 1.13 (1.03, 1.25) 0.012
Others/unknown 1.23 (1.14, 1.34) <0.001 1.21 (1.12, 1.32) <0.001

The multivariable models are additionally adjusted with variables such as year of cancer diagnosis, age at diagnosis, race, ethnicity, insurance, SES, cigarette use, SEER stage, histology, surgery as a treatment received, radiation therapy received, and chemotherapy received. Estimates for the variables used for adjustment were provided in Supplementary Table 1 .

–, not applicable; HR, hazard ratio; aHR, adjusted hazard ratio; 95% CI, 95% confidence interval.