Table 6.
The Multivariate Analysis of the Biological Variables
Table Analyzed | Multiple Regression of Biological Variables | ||||||
---|---|---|---|---|---|---|---|
Dependent variable | PVT | ||||||
Regression type | Least squares | ||||||
Model | |||||||
Analysis of Variance | SS | DF | MS | F (DFn, DFd) | P value | ||
Regression | 27.74 | 4 | 6.934 | F (4, 95) = 263.1 | P<0.0001 | ||
D-dimers | 0.1855 | 1 | 0.1855 | F (1, 95) = 7.038 | P = 0.0094 | ||
CRP | 0.4661 | 1 | 0.4661 | F (1, 95) = 17.69 | P<0.0001 | ||
TNF-alpha | 6.900 | 1 | 6.900 | F (1, 95) = 261.8 | P<0.0001 | ||
LPS | 0.01681 | 1 | 0.01681 | F (1, 95) = 0.6378 | P = 0.4265 | ||
Residual | 2.504 | 95 | 0.02635 | ||||
Total | 30.24 | 99 | |||||
Parameter estimates | Variable | Estimate | Standard error | 95% CI (asymptotic) | |t| | P value | P value summary |
β0 | Intercept | −0.5908 | 0.08784 | −0.7652 to −0.4164 | 6.726 | <0.0001 | **** |
β1 | D-dimers | 0.1945 | 0.07330 | 0.04894 to 0.3400 | 2.653 | 0.0094 | ** |
β2 | CRP | 0.1494 | 0.03552 | 0.07887 to 0.2199 | 4.206 | <0.0001 | **** |
β3 | TNF-alpha | 0.1691 | 0.01045 | 0.1484 to 0.1899 | 16.18 | <0.0001 | **** |
β4 | LPS | 0.007304 | 0.009146 | −0.01085 to 0.02546 | 0.7986 | 0.4265 | ns |
Goodness of Fit | |||||||
Degrees of Freedom | 95 | ||||||
R squared | 0.9172 |
Notes: **Medium/high statistical significance, ****Very high statistical significance.
Abbreviations: PVT, portal vein thrombosis; CRP, C-reactive protein; TNF, tumor necrosis factor; LPS, lipopolysaccharides; ns, not statistically significant.