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[Preprint]. 2023 Aug 22:2023.08.21.23294380. [Version 1] doi: 10.1101/2023.08.21.23294380

Table 5: Cumulative health outcomes and costs over the intervention period by program.

Values are the mean, minimum, and maximum values of the 859 accepted parameter sets. Health outcomes and costs are summed over the 10-year intervention period for a population of 100,000 individuals. Discounted values are presented in 2018 values and use an annual discount rate of 3%.

Program 1
Standard facility-based ART and TPT care
Program 2
Community-based ART care with standard facility-based TPT care
Program 3
Community-based ART with TPT care
Mean [Min, Max] Mean [Min, Max] Mean [Min, Max]
Health Outcomes and Costs (Undiscounted)
DALYs (thousands) 82.0 [70.5, 92.2] 59.7 [52.4, 67.2] 59.5 [52.2, 66.9]
TB incident cases (thousands) 12.7 [10.5, 14.7] 10.0 [8.1, 12.1] 9.7 [8.1, 11.6]
TB deaths (thousands) 1.8 [1.4, 2.3] 1.3 [1.0, 1.7] 1.3 [1.0, 1.7]
Program costs (millions in USD) 99.3 [90.6, 114.1] 118.2 [107.4, 135.5] 118.4 [107.6, 135.8]
Health Outcomes and Costs (Discounted)
DALYs (thousands) 73.4 [63.1, 82.5] 53.8 [47.1, 60.5] 53.6 [47, 60.2]
TB incident cases (thousands) 11.2 [9.2, 12.9] 8.8 [7.2, 10.7] 8.6 [7.1, 10.3]
TB deaths (thousands) 1.6 [1.2, 2] 1.2 [0.9, 1.5] 1.1 [0.9, 1.5]
Program costs (millions in USD) 87.1 [79.5, 100.1] 103.7 [94.3, 118.9] 103.9 [94.4, 119.2]