Figure 3: PGS associations with bone marrow biopsy outcomes.
(a) Distribution of the PGSWBC values among 117 BioVU participants who underwent a bone marrow biopsy for a clinical indication that included a low WBC count. Results are stratified by whether the biopsy identified pathology (abnormal, n=35) or not (normal, 82). (b) Predicted probabilities of a normal biopsy finding. Results are stratified by whether the indication for the biopsy include other hematological abnormalities in addition to a low WBC count. Probabilities are based on a multivariable logistic regression model, adjusted for age, sex and presence of a hematological abnormality.