Figure 2.

PRS prediction of asthma in white British UKB participants

(A) Odds ratios (ORs) with 95% CIs of asthma risk for individuals in different GBMI PRS quantiles relative to those with scores in the 40^th–60^th quantile.

(B) Density plot showing distributions of PRS scores by asthma status, with mean scores indicated by vertical lines.

(C) ORs with 95% CIs of COA and AOA risk for individuals in different PRS quantiles relative to those with scores in the 40^th–60^th quantile.

(D) Receiver-operating-characteristic curves for the PRS as a predictor of asthma, COA, and AOA.