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. 2023 Aug 17;4(4):100233. doi: 10.1016/j.xhgg.2023.100233

Figure 7.

Figure 7

Changes in asthma PRS associations after removing HLA region

Changes in PRS association effect sizes after removing the HLA region from the PRS (Δβ) are shown with 95% confidence intervals for traits with significant effect reductions and for COA and AOA. Traits with a negative Δβ had a weaker association with the asthma PRS, and traits with a positive Δβ had a stronger association with the asthma PRS after removing HLA region alleles from consideration.