Table 2.

ITT analysis results for number of intrusive memories (treatment effects for between-arm comparison of primary outcome, and within delayed arm comparison of secondary outcome).

Number of Intrusive Memories (IMs)	Delayed arm (n = 39)		Immediate arm (n = 36)		ITT Treatment Effect Estimate
					IRR	95% CI
Primary Outcome (Week 4) – Between Arm Comparison
Median, IQR	10.00	(6.0, 17.0)	1.00	(0.0, 3.0)	0.31***	0.20, 0.48
Mean, SD	12.46	9.28	4.03	10.68
Secondary Outcome (Week 8, after crossovera) - Within Delayed Arm Comparison
Median, IQR	1.00	(0.0, 2.50)			0.31***	0.21, 0.45
Mean, SD	3.78	7.23
Baseline/Run-In Week
Median, IQR	14.00	(8.0, 19.0)	14.50	(10.0, 21.50)
Mean, SD	17.08	15.84	18.50	13.61

Treatment effects presented for between-arm comparison of number of intrusive memories at week 4 (primary outcome), and within delayed arm comparison of number of intrusive memories at week 8 (after crossover) from week 4. Median (IQR) and Mean (s.d.) of number of intrusive memories at baseline, week 4, and week 8 are also presented.

ITT intention to treat, IRR incidence rate ratio, CI confidence interval, IQR interquartile range, SD standard deviation.

***p < 0.001;

^aITT treatment effect estimate within the delayed arm after crossover (weeks 4–8).