Table 1.
Results of conjunctional FDR showing number of shared loci between AN and related disorders and psychological traits.
| Secondary phenotype | Secondary GWAS (n/neffective for case-control GWASs)1 | Shared loci with AN at conjFDR < 0.05 | Novel loci in AN (n) | Novel loci in comparison phenotype (n) |
|---|---|---|---|---|
| SCZ | 126,282 | 20 | 18 | 4 |
| BIP | 150,670 | 10 | 10 | 3 |
| MD | 389,039 | 20 | 19 | 9 |
| Mood | 356,933 | 13 | 12 | 4 |
| NEUR | 372,903 | 29 | 26 | 7 |
| INT | 269,867 | 36 | 31 | 16 |
Note: AN Anorexia nervosa, BIP Bipolar disorder, conjFDR Conjunctional False Discovery Rate, INT Intelligence, Mood Mood instability, NEUR Neuroticism, SCZ Schizophrenia. 1neffective = 4/(1/ncases + 1/ncontrols).