Table 2.
Lead SNPs from 64 genome-wide significant (P-value <5 × 10-8) SNPs.
| Lead SNP | Chr | BP (b37) | Gene | Consequences | EA | NEA | Beta | SE | EAF | P-value | AF-EUR | AF-EAS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| rs59288815 | 10 | 61,846,677 | ANK3 | Intronic variant | C | T | 3.06e-01 | 5.55e-02 | 0.053 | 3.88e-08 | 0.00 | 0.00 |
| rs4277141 | 11 | 5,426,910 | OR51B5 | Intronic variant | A | G | −1.32e-01 | 2.340e-02 | 0.21 | 1.93e-08 | 0.49 | 0.149 |
| rs911119 | 20 | 23,612,737 | CST3 | Intronic variant | C | T | −1.74e-01 | 1.94e-02 | 0.616 | 3.51e-19 | 0.23 | 0.12 |
chr: chromosome, BP: base position, EA: effect allele, NEA: non effect allele, SE: standard error, EAF: effect allele frequency, MAF: minor allele frequency, AF_EUR: allele frequency in Europeans, AF-EA: allele frequency in East Asians.