Table 4.
Comparison of lead SNPs obtained from the UGR GWAS eGFRcys with UGR GWAS eGFRcrea.
| Gene | Lead SNP | Chr | Bp(b37) | EA | NEA | eGFRcys (Uganda) |
eGFRcrea (Uganda) |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Beta | SE | EAF | P-value | Beta | SE | EAF | P-value | ||||||
| OR51B5 | rs4277141 | 11 | 5,426,910 | A | G | −1.32e-01 | 2.340e-02 | 0.21 | 1.93e-08 | −5.71e-02 | 3.15e-02 | 0.208 | 6.97e-02 |
| CST3 | rs911119 | 20 | 23,612,737 | C | T | −1.74e-01 | 1.94e-02 | 0.616 | 3.51e-19 | −3.95e-04 | 2.63e-02 | 0.608 | 9.87e-01 |
| ANK3 | rs59288815 | 10 | 61,846,677 | C | T | 3.06e-01 | 5.55e-02 | 0.053 | 3.88e-08 | 6.33e-03 | 7.16e-02 | 0.056 | 9.28e-01 |