Table 3.
Clinical characteristics of individual PG patients.
| Patient | Age at TPC (years) | Sex | Pouchitis classification | Surgical technique | PG site | PG context | PG treatment | PG resolution | Pouch failure |
|---|---|---|---|---|---|---|---|---|---|
| A | 47 | Female | CLDP | Modified 2-stage | Peristomal | After colectomy | Prednisone, cyclosporine | Resolved | Failed, diverted |
| B | 49 | Male | CLDP | 3-stage | Peristomal | After IPAA | NA | Resolved | Failed, diverted |
| C | 31 | Female | No pouchitis | 3-stage | Peristomal | After colectomy, recurred after IPAA with diversion | 1st PG: Prednisone, cyclosporine 2nd PG: infliximab, stoma closure |
Resolved | Intact |
| D | 36 | Female | No pouchitis | Modified 2-stage | Peristomal | After colectomy | Prednisone, Stoma closure | Resolved | Intact |
| E | 36 | Male | CLDP | Modified 2-stage | Peristomal | After colectomy, recurred after permanent diversion for management of medically refractory CLDP | 1st PG: cyclosporine, prednisone, stoma closure recurrent PG: dapsone, intralesional triamcinolone, prednisone, adalimumab, infliximab, ustekinumab | Not Resolved | Failed, diverted |
| F | 23 | Female | CLDP | 3-stage | Peristomal | After diversion ileostomy for medically refractory CLDP, subsequently underwent pouch excision | Intralesional triamcinolone, adalimumab | Resolved | Failed, excised |
| G | 44 | Female | CLDP | 2-stage | Peristomal | After diversion ileostomy for medically refractory CLDP | Prednisone, intralesional triamcinolone | Resolved | Failed, diverted |
| H | 25 | Female | CLDP | Modified 2-stage | Peristomal, Lower extremity | Peristomal PG after pouch excision, unclear when lower extremity PG initially diagnosed | Intralesional triamcinolone, dapsone | NA | Failed, excised |
| I | 33 | Male | CLDP | 3-stage | Peristomal | After diversion ileostomy for medically refractory CLDP, subsequently underwent pouch excision | Intralesional triamcinolone | Resolved | Failed, excised |
| J | 50 | Male | Antibiotic-responsive | 2-stage | Lower extremity | Before colectomy | Infliximab, adalimumab, ustekinumab | Not Resolved | Intact |
Abbreviations: CLDP, Crohn’s-like disease of the pouch; IPAA, ileal pouch anal anastomosis; IQR, interquartile range; PG, pyoderma gangrenosum; TPC, total proctocolectomy.