Table 4.

Univariable penalized logistic regression to evaluate predictors of pouch failure among patients who develop PG prior to pouchitis.

Characteristic	N	Event N	OR	95% CI	P value	Q valuea
Presence of PG	339	18	20.7	3.9, 110.7	<.001	0.003
Pre-colectomy tobacco use	339	18
Active			—
Former			0.7	0.2, 2.8	.582	0.582
Never			0.5	0.1, 1.9	.296	0.414
Post-colectomy tobacco use	339	18
Active			—
Former			0.3	0.1, 0.9	.039	0.090
Never			0.2	0.1, 0.6	.006	0.020
Age at colectomy	339	18	1.0	0.9, 1.0	.170	0.298
PSC	339	18	0.4	0.1, 3.4	.438	0.511

Abbreviations: Cl, confidence interval; OR, odds ratio; PG, pyoderma gangrenosum; PSC, primary sclerosing cholangitis.

^aFalse discovery rate correction for multiple testing.