Table 3.
Comprehensive account of some synthetic and natural polymers that have been recently utilized in the fabrication of biocompatible HA composite scaffolds.
| Polymer and Additives | Crosslinker | Fabrication Method | In Vitro Study | In Vivo Study | Refs |
|---|---|---|---|---|---|
| Col, Zinc, Silicate | Genipin 1 wt% | 3D Printing | BMSCs | Rat (critical size calvarial defect) | [113] |
| Alg, PVA | cacl2 100 mM solution | 3D Printing | MC 3T3 | – | [114] |
| PCL | – | 3D Printing | Osteoblast Cell | Rat (calvarial defect) | [115] |
| PCL, MgO | – | 3D Printing | MC 3T3-E1 | – | [116] |
| PLA, Alg | – | 3D Printing | – | – | [117] |
| PLA, Silk | – | 3D Printing | – | – | [118] |
| PLA | – | 3D Printing | BMSCs | – | [119] |
| PLA | – | 3D Printing | BMSCs | White rabbits (Tibial periosteum defect) | [120] |