Fig. 2.

In-vivo experimental setup and imaging protocol. (a) Imaging setup and major components, (b) schematic of TFPAI probe components and optical fiber configuration, (c) schematic of sheep brain sagittal and coronal view demonstrating the location of the blood sample injection pathway to induce hemorrhage, (d) confirmation of needle insertion into a ventricle through release of CSF, (e) photograph of injection of arterial blood sample, and (f) overall imaging protocol. CC: corpus callosum; LV: lateral ventricles; SC: spinal cord; Po: pons; M: Medulla; TH: thalamus; CSF: cerebrospinal fluid.