. Author manuscript; available in PMC: 2024 Jul 1.

Published in final edited form as: Brain Behav Immun. 2023 Mar 29;111:116–123. doi: 10.1016/j.bbi.2023.03.024

Table 2.

LPS-stimulated cytokine and Cortisol values in female participants with IC/BPS and female healthy community participants. There were no differences in levels of stimulated analytes or cortisol measures between groups by Mann-Whitney U tests (all p> .05).

	IC/PBS (n=154)		Healthy Controls (N=32)
Cytokine (Stimulated: pg/ML)	Median	25^th – 75^th Percentile	Median	25^th – 75^th Percentile

Monocyte chemoattractant protein-1 (MCP-1)	1524.65	985.18 – 2313.23	1520.90	1059.18–2143.93
Macrophage inflammatory protein 1-alpha (MIP1α)	44443.55	33012.63 – 67268.13	60742.80	35883.1077066.73
Interleukin-1 beta (IL-1β)	8311.30	4157.50 – 12244.05	7949.60	3419.35–11966.80
Interleukin-6 (IL-6)	19244.70	13294.00 – 24990.30	20156.00	14892.5023882.25
Interleukin-8 (IL-8)	12451.10	8926.20 – 19456.20	11846.30	8661.50–17428.55
Interleukin-10 (IL-10)	64.80	35.35 – 94.40	58.31	24.85–82.90
Tumor necrosis factor-alpha (TNF-α)	3910.10	2540.40 – 5480.30	4002.90	2778.70–5949.90

Cortisol
Morning mean nmol/L (n=103)	7.55	5.11 – 9.86	7.75	5.22–9.98
Nocturnal nmol/L (n=118)	0.92	.64 −1.55	1.11	.80–2.17
Slope (n=97)	−0.148	−.18 - −0.09	−0.123	−0.185- −0.057

Note: All values are raw values.

pg/mL= picograms/liter nmol/L= nanamole/liter