Table 3.
Association between PD-L1 expression and clinicopathological characteristics
| PD-L1 expression | P | ||
|---|---|---|---|
|
Negative CPS (< 10%) N = 58 n, (%) |
Positive CPS (≥ 10%) N = 43 n, (%) |
||
| Age | |||
| < 71 years | 22 (44.9) | 18 (52.9) | 0.376 |
| ≥ 71 years | 27 (55.1) | 16 (47.1) | |
| Sex | |||
| Male | 36 (73.5) | 26 (76.5) | 0.803 |
| Female | 13 (26.5) | 8 (23.5) | |
| Smoking status | |||
| Smoker | 37 (78.7) | 26 (83.9) | 0.770 |
| Non-smoker | 10 (21.3) | 5 (16.1) | |
| Stage group | |||
| Stage II | 22 (44.9) | 10 (29.4) | 0.307 |
| Stage III | 6 (12.2) | 7 (20.6) | |
| Stage IV | 21 (42.9) | 17 (50) | |
| Metastatic site | |||
| Lungs | 6 (12.2) | 3 (8.8) | 0.731 |
| Bones | 5 (10.2) | 2 (5.9) | 0.695 |
| Other | 5 (10.2) | 5 (14.7) | 0.733 |
| Previous treatment | |||
| BCG (+) | 11 (68.8) | 7 (58.3) | 0.698 |
| BCG (-) | 5 (31.3) | 5 (41.7) | |
| Chemotherapy (+) | 5 (33.3) | 5 (41.7) | 0.706 |
| Chemotherapy (-) | 10 (66.7) | 7 (58.3) | |
| Histologic type | |||
| Conventional UC | 55 (95) | 38 (88) | 0.28 |
| UC of special variant | 3 (5) | 5 (12) | |
| Inflexion/histologic differentiation | |||
| Squamous | 15 (26) | 10 (23) | 0.803 |
| Glandular | 8 (14) | 3 (7) | 0.187 |
| Micropapillary | 8 (14) | 3 (7) | 0.695 |
| Sarcomatoid | 0 | 3 (7) | 0.165 |
| With signet-ring cells | 0 | 1 (2) | 0.410 |
| Microcystic | 0 | 1 (2) | 0.410 |
| Molecular subtype | |||
| Basal | 14 (64) | 12 (719) | 0.467 |
| Luminal | 7 (32) | 4 (23) | |
Abbreviations: BCG Bacillus Calmette-Guerin, UC Urothelial carcinoma