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. 2023 Sep 2;28:319. doi: 10.1186/s40001-023-01257-6

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Resveratrol modulates the arginine/proline metabolic pathway. A Hierarchical clustering heatmap of significantly differential metabolites in negative ion mode. B Hierarchical clustering heatmap of significantly differential metabolites in positive ion mode. C Differential metabolite network diagram between the RSV group and the DSS group in positive ion mode. D KEGG enrichment pathway diagram (bubble diagram). E Differential abundance score plot of all enriched metabolic pathways between the RSV group and the DSS group. F Clustering heatmap of differential metabolites in the KEGG pathway for arginine and proline metabolism between the DSS and the RSV groups. G KEGG pathway diagram of arginine and proline metabolism containing differential metabolites