Table 3.
Spearman correlation between log-transformed PFAS (ng/ml) and gestational weight gain (kg) in the UPSIDE cohort
| Group | Term | PFOS | PFOA | PFNA | PFHxS | PFDA |
|---|---|---|---|---|---|---|
| All participants (n = 243) | Trimester 2 GWG | 0.09 | -0.00 | -0.00 | 0.13* | 0.11 |
| Trimester 3 GWG | 0.01 | -0.02 | 0.01 | -0.03 | 0.08 | |
| Mid/late GWG | 0.06 | -0.02 | 0.01 | 0.06 | 0.11 | |
| Total GWG | 0.09 | -0.00 | 0.03 | 0.08 | 0.14* | |
| Participants with pre-pregnancy BMI < 25 kg/m2 (n = 114) | Trimester 2 GWG | -0.13 | -0.14 | -0.25** | -0.00 | -0.20* |
| Trimester 3 GWG | -0.14 | -0.03 | -0.09 | -0.14 | -0.11 | |
| Mid/late GWG | -0.17 | -0.10 | -0.22 | -0.09 | -0.19* | |
| Total GWG | -0.20* | -0.15 | -0.25** | -0.13 | -0.20* | |
| Participants with pre-pregnancy BMI > = 25 kg/m2 (n = 129) | Trimester 2 GWG | 0.14 | 0.02 | 0.12 | 0.03 | 0.16 |
| Trimester 3 GWG | 0.07 | -0.04 | 0.06 | -0.02 | 0.16 | |
| Mid/late GWG | 0.12 | -0.01 | 0.10 | 0.01 | 0.19* | |
| Total GWG | 0.16 | 0.03 | 0.15 | 0.02 | 0.22* |
Abbr: BMI Body Mass Index, GWG gestational weight gain, PFAS per- and poly-fluoroalkyl substances, PFDA perfluorodecanoic acid, PFHxS perfluorohexanesulfonic acid, PFNA perfluorononanoic acid, PFOA perfluorooctanoic acid, PFOS perfluorooctanesulfonic acid
*indicates p < 0.05
**indicates p < 0.01