Table 2.
Resistance Rates of Enterobacteriaceae Strains to Antimicrobial Agents
| Antimicrobial Agent | KPN (n=9623) | ECO (n=5684) | ECL (n=1528) | SMA (n=727) | PMI (n=383) | CFR (n=240) | MMO (n=141) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R | S | R | S | R | S | R | S | R | S | R | S | R | S | |
| Ampicillin | –a | – | 86.7 | 11.9 | – | – | – | – | 64.9 | 32.9 | – | – | – | – |
| Piperacillin | 41.1 | 50.4 | 84.5 | 13.2 | 49.2 | 49.2 | 7.0 | 92.6 | 44.2 | 45.3 | 52.1 | 43.8 | 27.0 | 64.9 |
| Cefoperazone–sulbactam | 17.9 | 76.5 | 11.5 | 75.6 | 24.0 | 65.4 | 1.7 | 95.8 | 1.0 | 95.8 | 17.9 | 72.4 | 4.9 | 92.6 |
| Ampicillin–sulbactam | 33.3 | 61.3 | 51.2 | 28.6 | – | – | – | – | 42.2 | 49.4 | – | – | 64.8 | 9.0 |
| Piperacillin–tazobactam | 16.1 | 80.0 | 8.6 | 86.1 | 27.3 | 63.7 | 2.6 | 94.8 | 0.5 | 98.6 | 22.9 | 64.7 | 3.7 | 94.8 |
| Cefazolin | 42.1 | 45.7 | 72.5 | 17.2 | – | – | – | – | 59.3 | 25.0 | – | – | – | – |
| Cefuroxime | 33.6 | 63.5 | 60.2 | 36.1 | 63.3 | 23.6 | – | – | 46.9 | 50.2 | – | – | – | – |
| Ceftazidime | 21.8 | 76.5 | 30.4 | 66.7 | 43.4 | 55.5 | 4.3 | 95.1 | 6.8 | 91.6 | 44.2 | 54.5 | 15.2 | 78.0 |
| Ceftriaxone | 30.9 | 68.9 | 59.6 | 40.2 | 48.6 | 50.4 | 10.9 | 86.8 | 40.8 | 57.0 | 47.8 | 51.3 | 16.9 | 77.9 |
| Cefepime | 19.2 | 77.3 | 24.4 | 66.7 | 23.2 | 69.3 | 3.3 | 93.8 | 10.4 | 73.9 | 17.1 | 78.2 | 5.4 | 90.8 |
| Cefoxitin | 20.8 | 77.1 | 14.4 | 80.0 | – | – | – | – | 4.2 | 93.2 | – | – | 18.6 | 60.5 |
| Ertapenem | 9.0 | 90.9 | 2.9 | 96.9 | 15.3 | 83.1 | 2.9 | 96.8 | 1.0 | 97.9 | 7.9 | 91.5 | 2.8 | 97.2 |
| Imipenem | 12.6 | 86.7 | 3.4 | 96.4 | 16.3 | 81.5 | 5.8 | 84.1 | 25.0b | 50.0 b | 10.0 | 87.3 | NA | NA |
| Meropenem | 14.1 | 85.6 | 3.6 | 96.1 | 14.1 | 85.1 | 2.4 | 97.1 | 0.9 | 98.3 | 10.8 | 88.6 | 2.3 | 97.7 |
| Amikacin | 9.8 | 90.0 | 2.7 | 96.9 | 2.5 | 96.0 | 0.3 | 99.3 | 1.9 | 97.3 | 1.3 | 98.7 | 4.3 | 95.7 |
| Gentamicin | 18.6 | 80.3 | 34.9 | 63.3 | 18.0 | 76.9 | 2.2 | 97.2 | 20.0 | 56.0 | 17.3 | 81.0 | 21.8 | 72.2 |
| Ciprofloxacin | 21.1 | 76.6 | 52.5 | 45.1 | 20.3 | 75.0 | 1.7 | 97.7 | 42.4 | 51.0 | 25.3 | 70.6 | 20.5 | 68.2 |
| Levofloxacin | 18.7 | 78.8 | 50.3 | 46.6 | 18.3 | 77.0 | 1.0 | 98.1 | 25.2 | 64.1 | 20.1 | 75.1 | 9.0 | 81.3 |
| Trimethoprim–sulfamethoxazole | 24.5 | 75.5 | 52.7 | 47.2 | 25.9 | 74.1 | 2.8 | 97.2 | 54.9 | 45.1 | 25.0 | 75.0 | 37.0 | 63.0 |
| Polymyxin B | 0.8 | 95.1 | 2.3 | 97.7 | 0.0 | 90.9 | – | – | – | – | 0.0 | 100.0 | – | – |
| Tigecycline | 1.8 | 96.7 | 0.2 | 99.8 | 2.0 | 95.7 | 0.3 | 98.7 | – | – | 1.0 | 98.0 | – | – |
| Nitrofurantoin | 30.8 | 28.3 | 3.1 | 88.4 | 17.2 | 33.4 | – | – | – | – | 3.9 | 92.2 | – | – |
| Fosfomycin | NA | NA | 2.0c | 96.0c | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Notes: aIntrinsic resistance; bResults by Kirby–Bauer method only; cFor urinary tract isolates only.
Abbreviations: NA, not available; KPN, Klebsiella pneumonia; ECO, Escherichia coli; ECL, Enterobacter cloacae; SMA, Serratia marcescens; PMI, Proteus mirabilis; CFR, Citrobacter freundii; MMO, Morganella morganii.