Table 2.

Relative abundance (≥ 1%) at genus levels in patients with SVR and non-SVR at baseline and FUw72.

Genus	SVR (n = 66)		P-values	Non-SVR (n = 3)		P-values
	Baseline	FUw72		Baseline	FUw72
Increasing bacteria in SVR group
Blautia	0.018 ± 0.02	0.073 ± 0.04	< 0.001**	0.017	0.069	0.109
Bifidobacterium	0.002 ± 0.01	0.028 ± 0.06	< 0.001**	0.006	0.104	0.109
Subdoligranulum	0.003 ± 0.01	0.012 ± 0.02	< 0.001**	0.025	0.014	0.593
Dorea	0.005 ± 0.00	0.014 ± 0.01	< 0.001**	0.006	0.013	0.593
Megamonas	0.001 ± 0.01	0.007 ± 0.06	0.002*	0.019	0.059	1.000
Collinsella	0.000 ± 0.00	0.043 ± 0.02	< 0.001**	0.000	0.019	0.285
Ruminococcus torques group	0.004 ± 0.01	0.014 ± 0.02	< 0.001**	0.011	0.022	1.000
Fusicatenibacter	0.002 ± 0.01	0.013 ± 0.02	< 0.001**	0.014	0.031	0.109
Streptococcus	0.001 ± 0.00	0.006 ± 0.01	< 0.001**	0.001	0.013	0.285
Eubacterium hallii group	0.003 ± 0.00	0.014 ± 0.01	< 0.001**	0.003	0.019	0.109
Coprococcus	0.003 ± 0.01	0.010 ± 0.02	< 0.001**	0.009	0.012	1.000
Anaerostipes	0.001 ± 0.00	0.006 ± 0.01	< 0.001**	0.002	0.014	0.109
Megasphaera	0.000 ± 0.00	0.000 ± 0.01	0.006*	0.004	0.024	1.000
Holdemanella	0.000 ± 0.00	0.000 ± 0.02	0.004*	0.000	0.032	0.180
Decreasing bacteria in SVR group
Bacteroides	0.170 ± 0.33	0.090 ± 0.14	< 0.001**	0.087	0.155	0.593
Lachnoclostridium	0.013 ± 0.02	0.009 ± 0.02	0.034*	0.024	0.012	0.109
Sutterella	0.015 ± 0.02	0.010 ± 0.01	0.036*	0.023	0.014	0.593
Lachnospira	0.007 ± 0.01	0.004 ± 0.01	0.033*	0.016	0.008	0.285
Eubacterium eligens group	0.006 ± 0.01	0.002 ± 0.01	0.002*	0.011	0.000	0.180

Data shown in median ± IQR

SVR, Sustained virological response rates; FUw72, follow-up week-72

*P < 0.05, **P < 0.001 (Wilcoxon Signed Ranks Test)