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. 2023 Sep 2;13:14484. doi: 10.1038/s41598-023-41765-3

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© The Author(s) 2023, corrected publication 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Visualization of the concentration change over the course of simulation in each of the modeled pathways: (a) TCA cycle, (b) Glycolysis, (c) pentose phosphate pathway, (d) beta-oxidation. The X-axis displays number of measurements. During 10,000 seconds of simulation, concentration was measured 50,000 times. The Y-axis displays the concentration of a given metabolite.