Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Sep 2;14:5355. doi: 10.1038/s41467-023-41121-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 7 — a Treatment schedule of COF-919-mediated phototherapy. Tumor volumes (b), body weights (c), and tumor images (d) of 4T1 tumor-bearing mice treated under different conditions; data are presented as mean ± SEM (n = 5 independent samples). Quantitative evaluation of Ki67(e) and 4-HNE (f); data are presented as mean ± SEM (n = 5 independent samples). g Western blot analysis was performed to determine the GPX4 and GSDME-N expression levels in tumor tissues; Western blot was done thrice independently with similar results. h Illustration of COF-919-mediated phototherapy to promote DC maturation. Quantitative evaluation of DCs in the DLN (m); T_CM (j), and T_EM (k) cells in the spleen; T_CM (n) and T_EM (o) cells in DLN; Tregs cells in the spleen (l) and DLN (p); MDSCs in the spleen (i); data are presented as mean ± SEM (n = 5 independent samples). Statistical significance was calculated via two-way ANOVA (b) and one-way ANOVA with Tukey’s multiple comparisons test (e, f, i–p). Source data are provided as a Source Data file.