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. 2023 Aug 30;16:703–721. doi: 10.2147/OTT.S416824

Figure 2.

Figure 2

Chidamide enhanced oxaliplatin-induced proliferation inhibition and apoptosis in HCT-116 and RKO cells. (A) Colony formation analyzed the effects of chidamide and oxaliplatin monotherapy and the combined treatment on HCT-116 and RKO cell proliferation. (B) CCK-8 analyzed the effects of chidamide and oxaliplatin monotherapy and the combined treatment on HCT-116 and RKO cell viability. (C) Flow cytometry analyzed the effects of chidamide and oxaliplatin monotherapy and the combined treatment on HCT-116 and RKO cell apoptosis. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.

Abbreviations: NC, negative control (0.1% DMSO); CHI, 4 μM chidamide; OXA, 8 μM oxaliplatin; CHI+OXA, 4 μM chidamide + 8 μM oxaliplatin.