Fig. 5.

Base-edited monkeys support tumor growth. a Schematic diagram illustrating the growth of human breast cancer cells in base-edited monkeys. b Fluorescence microscopy image displaying the GFP signal emitted by human breast cancer cells. c In vivo imaging of animals to observe the status of tumor. d Examination of tumor tissues in base-edited monkeys. e Immunofluorescence staining of tumor tissues indicating extensive expression of GFP protein. Scale bars: 4X: Tumor = 500 µm Control = 200 µm, 20X = 50 µm, 40X = 40 µm