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. 2023 Aug 21;10:1248321. doi: 10.3389/fmed.2023.1248321

Table 2.

Comparison of maternal characteristics between GA at delivery <26 weeks and ≥26 weeks.

GA at delivery <26 weeks (n = 17) GA at delivery ≥26 weeks (n = 18) p-value
Maternal age 33 [29–40] 36 [29–42] 0.02*
BMI 25.3 [19.5–38.0] 24.9 [22.5–28.6] 0.72
Parity
Primiparous 11/17 (64.7%) 11/18 (61.1%) 1
Multiparous 6/17 (35.3%) 7/18 (38.9%)
History of PTB 12/17 (70.6%) 15/18 (83.3%) 0.44
History of conization/LEEP 0/17 (0%) 1/18 (94.4%) 1
Mullerian anomaly 2/17 (11.8%) 0/18 (0%) 0.23
In vitro fertilization 3/17 (17.7%) 5/18 (27.8%) 0.69
Prior cerclage type
History-indicated cerclage 7/17 (41.2%) 13/18 (72.2%) 0.15
Ultrasound-indicated cerclage 4/17 (23.5%) 1/18 (5.6%)
Physical examination-indicated cerclage 6/17 (35.3%) 4/18 (22.2%)
GA at prior cerclage (weeks) 15 [13–20+1] 13+6 [12+5–18] 0.06
GA at repeat cerclage (weeks) 21 [16+2–23+4] 21+6 [16+2–23+6] 0.24
Latency between RC and prior cerclage 30 [8–66] 49 [5–76] 0.008*
Size of bulging membranes (cm) 2.7 [1.0–6.0] 2.1 [1.0–5.0] 0.12
Culture positive 10/17 (58.82%) 10/18 (55.56%) 1
NLR before RC 5.2 [2.8–12.3] 4.9 [3.0–18.0] 0.55
CRP before RC 5.8 [0.9–42.3] 6.0 [3.0–18.0] 0.44
NLR after RC 7.0 [2.9–12.7] 6.5 [1.9–69.5] 0.87
CRP after RC 11.2 [1.8–54.9] 19.2 [5.1–66.4] 0.21
Use of amniocentesis 6/17 (35.3%) 12/18 (66.7%) 0.094
Number of suture knots 13/17 (76.5%) 8/18 (44.4%) 0.11
Postoperative CL (mm) 13 [8–20] 22 [5–41] < 0.001*

Data are expressed as medians (ranges), and numbers (percentages).

*p < 0.05, which means statistical difference.

BMI, body mass index; GA, gestational age; RC, repeat cerclage; NLR, neutrophil lymphocyte ratio; CL, cervical length; PTB, preterm birth; CRP, c-reactive protein; LEEP, loop electrosurgical excision procedure.