Table 1. Association of physiological indexes with plaque vulnerability.
| Study | Publication year | Number of lesions (patients) | Prevalence of OCT-derived TCFAs, n (%) | p value | |
|---|---|---|---|---|---|
| Usui et al.47) | 2018 | 382 (340) | FFR >0.79 | 15 (11.7) | 0.02 |
| FFR 0.72–0.79 | 14 (10.8) | ||||
| FFR <0.72 | 27 (21.8) | ||||
| Hoshino et al.48) | 2020 | 473 (419) | FFR >0.80 & CFR >2.0 | 8 (7.8) | <0.01 |
| FFR >0.80 & CFR ≤2.0 | 6 (23.1) | ||||
| FFR ≤0.80 & CFR >2.0 | 14 (8.2) | ||||
| FFR ≤0.80 & CFR ≤2.0 | 38 (22.0) | ||||
| Zuo et al.49) | 2021 | 132 (126) | QFR >0.93 | 5 (19.2) | <0.01 |
| QFR 0.85–0.93 | 4 (13.8) | ||||
| QFR ≤0.85 | 14 (50.0) | ||||
CFR = coronary flow reserve; FFR = fractional flow reserve; OCT = optical coherence tomography; QFR = quantitative flow ratio; TCFA = thin cap fibroatheroma.