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. 2023 Jul 14;26(4):378–390. doi: 10.4048/jbc.2023.26.e31

Table 4. rs1047972 and rs8173 variants of the AURKA gene and their association with the breast cancer group.

Variant Genotype Variable OR (95% CI) p-value
rs1047972 CT Overweight 2.6 (1.26–5.67) 0.010
CTTT 2.3 (1.17–4.46) 0.016
CT Obesity 3.2 (1.60–6.66) 0.001
CTTT 2.5 (1.32–4.87) 0.005
CTTT Family history of cancer 1.9 (1.03–3.68) 0.038
CTTT Estrogen receptor plus obesity 2.5 (1.11–5.79) 0.027
CTTT Ki-67 (≥ 20%) plus family history of cancer 2.66 (1.14–6.2) 0.023
rs8173 CG Chemotherapy gastric toxicity 1.6 (1.05–2.46) 0.029
CGGG 1.7 (1.11–2.72) 0.015
CGGG Estrogen receptor plus chemotherapy gastric toxicity 2.0 (1.15–3.48) 0.013
CGGG Progesterone receptor plus chemotherapy gastric toxicity 2.6 (1.42–4.9) 0.002
CGGG Menopause plus chemotherapy gastric toxicity 2.0 (1.15–3.7) 0.014

p-value less than 0.05 considered statistically significant.

OR = odds ratio; CI =confidence intervals.