Table 5. Haplotype frequency of the rs1047972 and rs8173 variants of the AURKA gene in studied groups.
rs1047972 | rs8173 | BC (2n = 548) | Controls (2n = 446) | OR (95% CI) | p-value |
---|---|---|---|---|---|
C | C | 259 (47.3) | 218 (48.9) | 0.9 (0.73–1.20) | 0.629 |
C | G | 130 (23.7) | 138 (30.9) | 0.7 (0.53–0.93) | 0.014 |
T | C | 93 (17.0) | 51 (11.4) | 1.6 (1.11–2.32) | 0.010 |
T | G | 66 (12.0) | 41 (9.2) | 1.3 (0.88–2.02) | 0.162 |
All those frequencies < 0.03 were not taken into account for the analysis. Values are presented as number (%) not otherwise specified.
BC = breast cancer; OR = odds ratio; CI = confidence interval.