Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model of the mechanism of Fusobacterium nucleatum stimulating CXCL1 secretion from pancreatic cancer cells, leading to cancer progression through two pathways: first, in an autocrine manner, F. nucleatum promoted pancreatic cancer cell migration and invasion, which was confirmed by in vitro coculture experiments with F. nucleatum; second, in a paracrine manner, F. nucleatum suppressed tumor‐infiltrating CD8+ T cells by recruiting MDSCs in vivo experiments.
