Figure 4.

LDA reveals patient subgroups with distinct pharmacodynamics

(A) Heatmap showing the sample topic proportions (${\theta }_{dk}$) for each single topic (patients, n = 50). Patient 17-162-08 has only one sample at week 0, and thus it is not included. Missing samples are colored gray in the heatmap.

(B) Dynamics of sample topic proportions (${\theta }_{dk}$) of the three topics in the four patient subgroups across time.