Characterizing participant-specific postmeal glycemic responses
(A) The inferred glucose response half-life for each participant, defined as the model-predicted time it would take for glucose levels to fall to 0.5 mmol/L following a peak of 1 mmol/L. The boxplots represent the 25th, 50th (median), and 75th percentiles of the posterior distribution and the whiskers represent the 5th and 95th percentiles.
(B) The average meal glucose spike height calculated as the mean height over all meals consumed during the experiment.
(C) The average meal height as a function of the glucose meal response half-life. Points represent the mean posterior value for each participant.
(D) Average meal response profiles using the posterior mean parameter values.
(E and F) Examples comparing the CGM data (blue) with the model prediction incorporating circadian dynamics (black) plus meal consumption (orange) for two participants with overdamped and underdamped dynamics, respectively. The time stamps of meals are shown as dashed lines. Participant order is the same in Figures 3A, 3B, 4A, and 4B.
See also Figures S8 and S9.