Table 1.
Clinicopathological parameters of CRC patients with respect to preoperative CAR
Variable | Before PSM |
After PSM |
||||
---|---|---|---|---|---|---|
High CAR (≥0.038) | Low CAR (<0.038) | P-value | High CAR (≥0.038) | Low CAR (<0.038) | P-value | |
No. of patients | 144 | 176 | 93 | 93 | ||
Sex | ||||||
Male | 86 (59.7) | 81 (46.0) | 53 (57.0) | 53 (57.0) | ||
Female | 58 (40.3) | 95 (54.0) | 0.018 | 40 (43.0) | 40 (43.0) | >0.999 |
Age (yr) | 73.8±10.8 | 68.6±11.8 | <0.001 | 71.9±11.8 | 71.4±10.5 | 0.738 |
ASA PS classification | ||||||
I | 7 (4.9) | 25 (14.2) | 7 (7.5) | 2 (2.2) | ||
II | 87 (60.4) | 124 (70.5) | 58 (62.4) | 69 (74.2) | ||
III | 49 (34.0) | 27 (15.3) | 27 (29.0) | 22 (23.7) | ||
IV | 1 (0.7) | 0 (0) | <0.001 | 1 (1.1) | 0 (0) | 0.114 |
CEA (ng/mL) | ||||||
≤5 | 74 (51.4) | 123 (69.9) | 51 (54.8) | 55 (59.1) | ||
>5 | 70 (48.6) | 53 (30.1) | 0.001 | 42 (45.2) | 38 (40.9) | 0.657 |
CA19-9 (U/mL) | ||||||
≤35 | 114 (79.2) | 152 (86.4) | 76 (81.7) | 74 (79.6) | ||
>35 | 30 (20.8) | 24 (13.6) | 0.100 | 17 (18.3) | 19 (20.4) | 0.853 |
Tumor location | ||||||
Right-side | 52 (36.1) | 73 (41.5) | 34 (36.6) | 34 (36.6) | ||
Left-side | 92 (63.9) | 103 (58.5) | 0.358 | 59 (63.4) | 59 (63.4) | >0.999 |
Tumor size (mm) | ||||||
≤50 | 76 (52.8) | 149 (84.7) | 69 (74.2) | 68 (73.1) | ||
>50 | 68 (47.2) | 27 (15.3) | <0.001 | 24 (25.8) | 25 (26.9) | >0.999 |
Tumor histotype | ||||||
pap/tub | 133 (92.4) | 170 (96.6) | 89 (95.7) | 87 (93.5) | ||
muc/por/sig | 11 (7.6) | 6 (3.4) | 0.132 | 4 (4.3) | 6 (6.5) | 0.747 |
Lymphatic invasion | ||||||
No | 65 (45.1) | 104 (59.1) | 50 (53.8) | 47 (50.5) | ||
Yes | 79 (54.9) | 72 (40.9) | 0.014 | 43 (46.2) | 46 (49.5) | 0.769 |
Venous invasion | ||||||
No | 70 (48.6) | 118 (67.0) | 53 (57.0) | 54 (58.1) | ||
Yes | 74 (51.4) | 58 (33.0) | 0.001 | 40 (43.0) | 39 (41.9) | >0.999 |
Pathological stage | ||||||
0 | 5 (3.5) | 29 (16.5) | 5 (5.4) | 7 (7.5) | ||
I | 24 (16.7) | 56 (31.8) | 24 (25.8) | 23 (24.7) | ||
II | 68 (47.2) | 45 (25.6) | 35 (37.6) | 30 (32.3) | ||
III | 47 (32.6) | 46 (26.1) | <0.001 | 29 (31.2) | 33 (35.5) | 0.805 |
Postoperative complicationa | 13 (9.0) | 12 (6.8) | 0.533 | 7 (7.5) | 9 (9.7) | 0.795 |
Values are presented as number only, number (%), or mean±standard deviation.
CRC, colorectal cancer; CAR, C-reactive protein to albumin ratio; PSM, propensity score matching; ASA, American Society of Anesthesiologists; PS, physical status; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; pap, papillary; tub, tubular; muc, mucinous; por, poorly differentiated; sig, signet-ring cell.
Clavien-Dindo grade >II.