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. 2022 Jun 13;39(4):315–325. doi: 10.3393/ac.2022.00234.0033

Table 1.

Clinicopathological parameters of CRC patients with respect to preoperative CAR

Variable Before PSM
After PSM
High CAR (≥0.038) Low CAR (<0.038) P-value High CAR (≥0.038) Low CAR (<0.038) P-value
No. of patients 144 176 93 93
Sex
 Male 86 (59.7) 81 (46.0) 53 (57.0) 53 (57.0)
 Female 58 (40.3) 95 (54.0) 0.018 40 (43.0) 40 (43.0) >0.999
Age (yr) 73.8±10.8 68.6±11.8 <0.001 71.9±11.8 71.4±10.5 0.738
ASA PS classification
 I 7 (4.9) 25 (14.2) 7 (7.5) 2 (2.2)
 II 87 (60.4) 124 (70.5) 58 (62.4) 69 (74.2)
 III 49 (34.0) 27 (15.3) 27 (29.0) 22 (23.7)
 IV 1 (0.7) 0 (0) <0.001 1 (1.1) 0 (0) 0.114
CEA (ng/mL)
 ≤5 74 (51.4) 123 (69.9) 51 (54.8) 55 (59.1)
 >5 70 (48.6) 53 (30.1) 0.001 42 (45.2) 38 (40.9) 0.657
CA19-9 (U/mL)
 ≤35 114 (79.2) 152 (86.4) 76 (81.7) 74 (79.6)
 >35 30 (20.8) 24 (13.6) 0.100 17 (18.3) 19 (20.4) 0.853
Tumor location
 Right-side 52 (36.1) 73 (41.5) 34 (36.6) 34 (36.6)
 Left-side 92 (63.9) 103 (58.5) 0.358 59 (63.4) 59 (63.4) >0.999
Tumor size (mm)
 ≤50 76 (52.8) 149 (84.7) 69 (74.2) 68 (73.1)
 >50 68 (47.2) 27 (15.3) <0.001 24 (25.8) 25 (26.9) >0.999
Tumor histotype
 pap/tub 133 (92.4) 170 (96.6) 89 (95.7) 87 (93.5)
 muc/por/sig 11 (7.6) 6 (3.4) 0.132 4 (4.3) 6 (6.5) 0.747
Lymphatic invasion
 No 65 (45.1) 104 (59.1) 50 (53.8) 47 (50.5)
 Yes 79 (54.9) 72 (40.9) 0.014 43 (46.2) 46 (49.5) 0.769
Venous invasion
 No 70 (48.6) 118 (67.0) 53 (57.0) 54 (58.1)
 Yes 74 (51.4) 58 (33.0) 0.001 40 (43.0) 39 (41.9) >0.999
Pathological stage
 0 5 (3.5) 29 (16.5) 5 (5.4) 7 (7.5)
 I 24 (16.7) 56 (31.8) 24 (25.8) 23 (24.7)
 II 68 (47.2) 45 (25.6) 35 (37.6) 30 (32.3)
 III 47 (32.6) 46 (26.1) <0.001 29 (31.2) 33 (35.5) 0.805
Postoperative complicationa 13 (9.0) 12 (6.8) 0.533 7 (7.5) 9 (9.7) 0.795

Values are presented as number only, number (%), or mean±standard deviation.

CRC, colorectal cancer; CAR, C-reactive protein to albumin ratio; PSM, propensity score matching; ASA, American Society of Anesthesiologists; PS, physical status; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; pap, papillary; tub, tubular; muc, mucinous; por, poorly differentiated; sig, signet-ring cell.

a

Clavien-Dindo grade >II.