Table 2.
Clinicopathological parameters of CRC patients with respect to CAR at the 1st postoperative day
| Variable | Before PSM |
After PSM |
||||
|---|---|---|---|---|---|---|
| High CAR (≥2.007) | Low CAR (<2.007) | P-value | High CAR (≥2.007) | Low CAR (<2.007) | P-value | |
| No. of patients | 95 | 225 | 81 | 81 | ||
| Sex | ||||||
| Male | 45 (47.4) | 122 (54.2) | 43 (53.1) | 43 (53.1) | ||
| Female | 50 (52.6) | 103 (45.8) | 0.273 | 38 (46.9) | 38 (46.9) | >0.999 |
| Age (yr) | 74.0±11.2 | 69.7±11.6 | 0.002 | 72.4±11.1 | 73.5±10.4 | 0.511 |
| ASA PS classification | ||||||
| I | 7 (7.4) | 25 (11.1) | 7 (8.6) | 7 (8.6) | ||
| II | 50 (52.6) | 161 (71.6) | 45 (55.6) | 48 (59.3) | ||
| III | 38 (40.0) | 38 (16.9) | 29 (35.8) | 25 (30.9) | ||
| IV | 0 (0) | 1 (0.4) | <0.001 | 0 (0) | 1 (1.2) | 0.813 |
| CEA (ng/mL) | ||||||
| ≤5 | 46 (48.4) | 151 (67.1) | 44 (54.3) | 48 (59.3) | ||
| >5 | 49 (51.6) | 74 (32.9) | 0.002 | 37 (45.7) | 33 (40.7) | 0.634 |
| CA19-9 (U/mL) | ||||||
| ≤35 | 74 (77.9) | 192 (85.3) | 65 (80.2) | 66 (81.5) | ||
| > 35 | 21 (22.1) | 33 (14.7) | 0.141 | 16 (19.8) | 15 (18.5) | >0.999 |
| Tumor location | ||||||
| Right-side | 43 (45.3) | 82 (36.4) | 33 (40.7) | 28 (34.6) | ||
| Left-side | 52 (54.7) | 143 (63.6) | 0.168 | 48 (59.3) | 53 (65.4) | 0.517 |
| Tumor size (mm) | ||||||
| ≤50 | 54 (56.8) | 171 (76.0) | 51 (63.0) | 49 (60.5) | ||
| > 50 | 41 (43.2) | 54 (24.0) | 0.001 | 30 (37.0) | 32 (39.5) | 0.872 |
| Tumor histotype | ||||||
| pap/tub | 86 (90.5) | 217 (96.4) | 76 (93.8) | 76 (93.8) | ||
| muc/por/sig | 9 (9.5) | 8 (3.6) | 0.052 | 5 (6.2) | 5 (6.2) | >0.999 |
| Lymphatic invasion | ||||||
| No | 38 (40.0) | 131 (58.2) | 36 (44.4) | 32 (39.5) | ||
| Yes | 57 (60.0) | 94 (41.8) | 0.003 | 45 (55.6) | 49 (60.5) | 0.633 |
| Venous invasion | ||||||
| No | 45 (47.4) | 143 (63.6) | 41 (50.6) | 39 (48.1) | ||
| Yes | 50 (52.6) | 82 (36.4) | 0.009 | 40 (49.4) | 42 (51.9) | 0.875 |
| Pathological stage | ||||||
| 0 | 9 (9.5) | 25 (11.1) | 9 (11.1) | 4 (4.9) | ||
| I | 16 (16.8) | 64 (28.4) | 16 (19.8) | 16 (19.8) | ||
| II | 32 (33.7) | 81 (36.0) | 22 (27.2) | 37 (45.7) | ||
| III | 38 (40.0) | 55 (24.4) | 0.026 | 34 (42.0) | 24 (29.6) | 0.060 |
| Postoperative complicationa | 13 (13.7) | 12 (5.3) | 0.020 | 11 (13.6) | 2 (2.5) | 0.009 |
Values are presented as number only, number (%), or mean±standard deviation.
CRC, colorectal cancer; CAR, C-reactive protein to albumin ratio; PSM, propensity score matching; ASA PS, American Society of Anesthesiologists physical status; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; pap, papillary; tub, tubular; muc, mucinous; por, poorly differentiated; sig, signet-ring cell.
a
Clavien-Dindo grade >II.