Table 3.
Clinicopathological parameters of CRC patients with respect to CAR at the 7th postoperative day
| Variable | Before PSM |
After PSM |
||||
|---|---|---|---|---|---|---|
| High CAR (≥0.859) | Low CAR (<0.859) | P-value | High CAR (≥0.859) | Low CAR (<0.859) | P-value | |
| No. of patients | ||||||
| Sex | 75 | 245 | 72 | 72 | ||
| Male | 52 (69.3) | 115 (46.9) | 49 (68.1) | 54 (75.0) | ||
| Female | 23 (30.7) | 130 (53.1) | 0.001 | 23 (31.9) | 18 (25.0) | 0.460 |
| Age (yr) | 74.3±9.6 | 69.9±12.0 | 0.004 | 74.2±9.7 | 73.4±9.2 | 0.635 |
| ASA PS classification | ||||||
| I | 2 (2.7) | 30 (12.2) | 2 (2.8) | 1 (1.4) | ||
| II | 41 (54.7) | 170 (69.4) | 41 (56.9) | 42 (58.3) | ||
| III | 31 (41.3) | 45 (18.4) | 29 (40.3) | 29 (40.3) | ||
| IV | 1 (1.3) | 0 (0.0) | <0.001 | 0 (0.0) | 0 (0.0) | >0.999 |
| CEA (ng/mL) | ||||||
| ≤5 | 43 (57.3) | 154 (62.9) | 41 (56.9) | 39 (54.2) | ||
| >5 | 32 (42.7) | 91 (37.1) | 0.417 | 31 (43.1) | 33 (45.8) | 0.867 |
| CA19-9 (U/mL) | ||||||
| ≤35 | 64 (85.3) | 202 (82.4) | 61 (84.7) | 56 (77.8) | ||
| >35 | 11 (14.7) | 43 (17.6) | 0.725 | 11 (15.3) | 16 (22.2) | 0.393 |
| Tumor location | ||||||
| Right-side | 29 (38.7) | 96 (39.2) | 28 (38.9) | 28 (38.9) | ||
| Left-side | 46 (61.3) | 149 (60.8) | >0.999 | 44 (61.1) | 44 (61.1) | >0.999 |
| Tumor size (mm) | ||||||
| ≤50 | 48 (64.0) | 177 (72.2) | 46 (63.9) | 49 (68.1) | ||
| >50 | 27 (36.0) | 68 (27.8) | 0.194 | 26 (36.1) | 23 (31.9) | 0.725 |
| Tumor histotype | ||||||
| pap/tub | 71 (94.7) | 232 (94.7) | 68 (94.4) | 69 (95.8) | ||
| muc/por/sig | 4 (5.3) | 13 (5.3) | >0.999 | 4 (5.6) | 3 (4.2) | >0.999 |
| Lymphatic invasion | ||||||
| No | 35 (46.7) | 134 (54.7) | 33 (45.8) | 37 (51.4) | ||
| Yes | 40 (53.3) | 111 (45.3) | 0.236 | 39 (54.2) | 35 (48.6) | 0.617 |
| Venous invasion | ||||||
| No | 40 (53.3) | 148 (60.4) | 38 (52.8) | 45 (62.5) | ||
| Yes | 35 (46.7) | 97 (39.6) | 0.286 | 34 (47.2) | 27 (37.5) | 0.312 |
| Pathological stage | ||||||
| 0 | 6 (8.0) | 28 (11.4) | 6 (8.3) | 8 (11.1) | ||
| I | 14 (18.7) | 66 (26.9) | 13 (18.1) | 19 (26.4) | ||
| II | 32 (41.7) | 81 (33.1) | 30 (41.7) | 23 (31.9) | ||
| III | 23 (30.7) | 70 (28.6) | 0.297 | 23 (31.9) | 22 (30.6) | 0.510 |
| Postoperative complicationa | 17 (23.3) | 8 (3.3) | <0.001 | 16 (22.9) | 3 (4.2) | 0.001 |
Values are presented as number only, number (%), or mean±standard deviation.
CRC, colorectal cancer; CAR, C-reactive protein to albumin ratio; PSM, propensity score matching; ASA PS, American Society of Anesthesiologists physical status; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; pap, papillary; tub, tubular; muc, mucinous; por, poorly differentiated; sig, signet-ring cell.
a
Clavien-Dindo grade >II.