Table 4.
Clinical Outcomes: VM Compared With VPT
| Variable | VM (n = 1,824) | VPT (n = 1,824) | OR |
|---|---|---|---|
| KDIGO AKI stage | |||
| 1 | 110 (6.0) | 152 (8.3) | . . . |
| 2 | 65 (3.6) | 79 (4.3) | . . . |
| 3 | 209 (11.5) | 255 (14.0) | . . . |
| 2/3 | 274 (15.0) | 334 (18.3) | 1.27 (1.06-1.52) |
| AKI requiring dialysis | 120 (6.6) | 180 (9.9) | 1.56 (1.23-2.00) |
| Dialysis or in-hospital mortality | 331 (18.1) | 403 (22.1) | 1.28 (1.10-1.52) |
| In-hospital mortality | 245 (13.4) | 270 (14.8) | 1.12 (0.93-1.35) |
| Hospital length of stay, d | 11.1 ± 9.2 | 11.1 ± 9.2 | . . . |
| Hospital discharge location | |||
| Death | 245 (13.4) | 270 (14.8) | . . . |
| Home | 779 (42.7) | 787 (43.1) | . . . |
| Nursing home | 88 (4.8) | 108 (5.9) | . . . |
| Other | 52 (2.9) | 40 (2.2) | . . . |
| External | 123 (6.7) | 137 (7.5) | . . . |
| Hospital | 112 (6.1) | 74 (4.1) | . . . |
| Skilled nursing facility | 425 (23.3) | 408 (22.4) | . . . |
Data are presented as No. (%) or mean ± SD, unless otherwise indicated. AKI = acute kidney injury; KDIGO = Kidney Disease: Improving Global Outcomes; VM = vancomycin and meropenem; VPT = vancomycin and piperacillin-tazobactam.