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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Chemosphere. 2022 Dec 6;313:137469. doi: 10.1016/j.chemosphere.2022.137469

Figure 2.

Figure 2.

The multi-metal PC (PC2) was associated with the expression of NF-kB enriched genes. (A) Plot demonstrating the individual loading values of metals onto the principal component 2 (PC2) eigenvector, (B) Volcano plot demonstrating differentially expressed (BH p-value <0.1) genes in relation to the multi-metal PC, adjusted for maternal pre-pregnancy BMI, maternal smoking, maternal SES score and infant sex, with select significant genes highlighted, (C) a significantly enriched biological network identified in pathway analysis of genes that were differentially expressed in response to the multi-metal PC.