TABLE 3.
Bivariate and multivariate logistic regression analysis factors associated with successful tuberculosis treatment outcomes in Limpopo province from 2010 to 2018.
| Variables | COR | 95% Cl | p-value | AOR | 95% Cl | p-value |
|---|---|---|---|---|---|---|
| Outcomes at 6 months of treatment | ||||||
| Positive (smear or culture positive) | Ref. | - | - | - | - | - |
| Died | 0.0 | 0.0 | 0.996 | 2.2 | 0.0 | 0.991 |
| Loss to follow-up | 0.0 | 0.0 | 0.997 | 1098 | 0.0 | 0.994 |
| Transfer | 9.4 | 0.9–94.9 | 0.058 | 0.1 | 0.0–1.1 | 0.058 |
| Negative (2 consecutive cultures) | 9.8 | 2.7–34.7 | 0.001* | 0.1 | 0.3–0.4 | 0.001 |
| Registration year | ||||||
| 2010 | Ref. | - | - | - | - | - |
| 2011 | 2.5 | 0.4–16.9 | 0.339 | 0.4 | 0.1–2.6 | 0.339 |
| 2012 | 9.7 | 1.4–66.3 | 0.021* | 0.1 | 0.0–0.7 | 0.021 |
| 2013 | 4.5 | 0.8–25.0 | 0.090 | 0.2 | 0.0–1.3 | 0.090 |
| 2014 | 4.9 | 0.8–29.1 | 0.078 | 0.2 | 0.0–1.2 | 0.078 |
| 2015 | 1.6 | 0.3–9.7 | 0.583 | 0.6 | 0.1–3.6 | 0.583 |
| 2016 | 2.6 | 0.4–15.5 | 0.288 | 0.3 | 0.1–2.3 | 0.288 |
| 2017 | 6.2 | 0.8–48.1 | 0.076 | 0.2 | 0.0–1.2 | 0.076 |
| 2018 | 8.6 | 1.1–66.2 | 0.038* | 1.1 | 0.0–0.9 | 0.038 |
| Previous drug history | ||||||
| No | Ref. | - | - | - | - | - |
| Yes | 0.5 | 0.1–2.1 | 0.347 | 1.6 | 0.6–4.1 | 0.347 |
| Previous drug history | ||||||
| New | 0.0 | 0.0 | 0.999 | 0.5 | 0.1–2.1 | 0.987 |
| PTR1 | 0.0 | 0.0 | 0.999 | 0.0 | 0.0 | 0.855 |
| PTR2 | Ref | - | - | - | - | - |
| Patient category | ||||||
| New | Ref. | - | - | - | - | - |
| Other | 1.2 | 0.1–26.2 | 0.930 | 0.9 | 0.0–19.8 | 0.930 |
| Relapse | 0.7 | 0.2–2.4 | 0.522 | 1.5 | 0.4–5.5 | 0.522 |
| TF1 | 0.7 | 0.2–2.8 | 0.623 | 1.4 | 0.4–5.6 | 0.623 |
| TF2 | 0.6 | 0.1–3.0 | 0.500 | 1.8 | 0.3–9.6 | 0.500 |
| Pulmonary or extra-pulmonary | ||||||
| Pulmonary | Ref. | - | - | - | - | - |
| Extra pulmonary | 6 034 258 | 0.0 | 0.999 | 1.9 | 1.2–1.2 | - |
| Age group (years) | ||||||
| 0–19 | 0.1 | 0.0 | 0.997 | 6.9 | 0.0 | 0.993 |
| 20–39 | 0.5 | 0.1–1.6 | 0.665 | 2.2 | 0.6–7.6 | 0.229 |
| 40–59 | 0.7 | 0.2–2.3 | 0.528 | 1.5 | 0.4–5.3 | 0.528 |
| 60 | Ref. | - | - | - | - | - |
| Gender | ||||||
| Male | Ref. | - | - | - | - | - |
| Female | 2.1 | 1.1–3.9 | 0.021* | 0.5 | 0.3–0.9 | 0.021 |
, significant p ≤ 0.05.
Ref., Reference; COR, crude odd ratio; CI, confidence interval; AOR, adjusted odds ratio; p = 0.005; PT1, patient treatment regimen 1; PT2, patient treatment regimen 2; TF1, treatment failure after regimen 1; TF2, treatment failure after regimen 2.