Table 3.
Summary of Sputum Analyses Data
| Number of Participants | Finding | |
|---|---|---|
| NRTN level in sputum supernatant, ng/mL | 64 | 2.03 (1.29) |
| Total inflammatory cell count, x106 /mL | 64 | 2.81 (5.25) |
| Differentiation of sputum inflammatory cell | 64 | |
| Macrophages, % | 21.4 (13.0) | |
| Neutrophils, % | 49.5 (25.8) | |
| Lymphocytes, % | 1.5 (1.2) | |
| Eosinophils, % | 27.7 (28.4) | |
| Cytokine and extra cellular matrix levels in sputum supernatant | ||
| IL-4, ng/mL | 44 | 9.5 (8.0) |
| IL-5, ng/mL | 44 | 32.3 (7.4) |
| IL-13, ng/mL | 51 | 12.1 (1.7) |
| IL-6, ng/mL | 36 | 17.8 (19.6) |
| IFN-γ, ng/mL | 38 | 19.9 (7.5) |
| MMP-2, pg/mL | 33 | 398 (298) |
| MMP-9, pg/mL | 37 | 327 (705) |
Note: Data are presented as mean (standard deviation) of subjects.
Abbreviations: NRTN, neurturin; IL-, interleukin-; IFN-γ, interferon-gamma; MMP-, matrix metalloproteinase-.