Table 3.
Oxford scores related to clinical outcomes in multivariate analyses including treatment with immunosuppression in IgA nephropathy
Clinical Outcome After Immunosuppressiona | Clinical Outcome | No. of Papers | No. of Analyses | No. of Analyses with C | M | E | S | T | C | None of MESTC |
---|---|---|---|---|---|---|---|---|---|---|
Improved | ESKD | 4 | 7b | 3 | 0 | 0 | 2 | 6 | 1 | 0 |
ESKD with another end point | 2 | 2 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | |
Rate of eGFR decline | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | |
Other | 3 | 3 | 3 | 0 | 0 | 0 | 0 | 1 | 2 | |
Total: Improved | 10 | 13b | 9 | 0 | 1 | 2 | 8 | 3 | 3 | |
Not improved | ESKD | 2c | 2 | 2 | 0 | 0 | 0 | 2 | 0 | 0 |
ESKD with another end point | 4 | 4 | 3 | 1 | 0 | 1 | 3 | 1 | 0 | |
Other | 2c | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | |
Total: Not improved | 8c | 8 | 7 | 1 | 0 | 1 | 5 | 1 | 2 | |
Worse: Total | ESKD | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Not said | ESKD | 2 | 2 | 2 | 0 | 0 | 1 | 1 | 0 | 1 |
ESKD with another end point | 2 | 2 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | |
Other | 3 | 4d | 2 | 3 | 0 | 1 | 1 | 0 | 1 | |
Total: Not said | 7 | 8d | 5 | 3 | 0 | 2 | 3 | 0 | 3 | |
Overall total | 26c | 30b,d | 22 | 4 | 1 | 5 | 17 | 4 | 8 |
M, mesangial cellularity; E, endothelial hypercellularity; S, segmental sclerosis/capsular adhesion; T, tubular atrophy/interstitial fibrosis; C, (fibro) cellular crescents.
Details in Supplemental Table 5.
Four analyses in one paper.
Two outcomes in one paper.
Two analyses in one paper.