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. 2022 Jun 13;13(7):e00505. doi: 10.14309/ctg.0000000000000505

Table 2.

Diagnostic accuracy of predictive MRE scores for histologic fibrosis and inflammation, FibrosisMRE and MaRIA, respectively, for detection of moderate to severe fibrosis and inflammation and active inflammation

ROCAUC Cutoff Sensitivity Specificity
Fibrosis moderate/severe (FibrosisMRE) 0.910 ≥2.080 0.681 1.000
Fibrosis moderate/severe (MaRIA) 0.896 ≥8.857 0.958 0.733
Fibrosis moderate/severe (ADC) 0.894 ≥1.452 0.958 0.692
Inflammation mod/severe (MaRIA) 0.763 ≥18.085 0.731 0.686
Inflammation active (MaRIA) 0.966 ≥7.120 0.926 1.000

AUC, area under curve; ADC, apparent diffusion coefficient; MRE, magnetic resonance enterography; MaRIA, magnetic resonance index of activity; ROC, receiver operator characteristic.

FibrosisMRE was a very good predictor of moderate to severe histological fibrosis. MaRIA had excellent performance in detecting active histological inflammation.